Search results for "Hernia repair"

showing 10 items of 46 documents

Morphogenetically-Active Barrier Membrane for Guided Bone Regeneration, Based on Amorphous Polyphosphate

2017

We describe a novel regeneratively-active barrier membrane which consists of a durable electrospun poly(ε-caprolactone) (PCL) net covered with a morphogenetically-active biohybrid material composed of collagen and inorganic polyphosphate (polyP). The patch-like fibrous collagen structures are decorated with small amorphous polyP nanoparticles (50 nm) formed by precipitation of this energy-rich and enzyme-degradable (alkaline phosphatase) polymer in the presence of calcium ions. The fabricated PCL-polyP/collagen hybrid mats are characterized by advantageous biomechanical properties, such as enhanced flexibility and stretchability with almost unaltered tensile strength of the PCL net. The pol…

0301 basic medicineBone Regenerationcollagen-inducingBarrier membranePolymersPharmaceutical Science02 engineering and technologyMatrix (biology)chemistry.chemical_compoundMiceOsteogenesisPolyphosphatesDrug Discoverystromal cell-derived factor-1Pharmacology Toxicology and Pharmaceutics (miscellaneous)MC3T3-E1 cellsChemistrybiologizationAnatomy3T3 Cells021001 nanoscience & nanotechnology3. Good healthMembranetensile strength/resistanceAlkaline phosphataseCollagen0210 nano-technologyinorganic polyphosphateSurface PropertiesPolyestersArticleAngiopoietin-203 medical and health sciencesCalcification PhysiologicAnimalsHumansBone regenerationTissue EngineeringPolyphosphateMesenchymal stem cellMembrane ProteinsMembranes ArtificialMesenchymal Stem Cellspolypropylene mesh030104 developmental biologyGene Expression RegulationBiophysicsbiologization; hernia repair; inorganic polyphosphate; collagen-inducing; polypropylene mesh; tensile strength/resistance; stromal cell-derived factor-1; MC3T3-E1 cellsNanoparticlesWound healinghernia repairMarine Drugs
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Inguinal hernioplasty improves the quality of life in patients with cirrhosis.

2008

Abstract Background The optimal management of symptomatic inguinal hernia (SIH) in cirrhotics is still undefined. Both hernia and cirrhosis impair quality of life (QOL). The aim of this study was to evaluate QOL by a Short Form-36 (SF-36) questionnaire in cirrhotic patients undergoing inguinal hernioplasty. Methods Thirty-two cirrhotic patients undergoing inguinal hernioplasty were evaluated. They were classified according to Child's class and to the absence or presence of refractory ascites. The SF-36 questionnaire was administered the day before and 6 months after surgery. Global analyses of the 8 domains of SF-36 and of 2 comprehensive indexes of SF-36, Physical Component Summary (PCS) a…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosismedicine.medical_treatmentHernia InguinalQuality of lifemedicineHumansHerniaIn patientProspective StudiesInguinal hernioplastybusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseHernia repairhumanitiesOptimal managementSurgeryInguinal herniaSymptomatic inguinal hernia (SIH) Quality of life (QOL) Cirrhosis.Quality of LifeSurgerybusiness
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A minor modification of Lichtenstein repair of primary inguinal hernia: postoperative discomfort evaluation.

2010

The aim of this study was to evaluate the usefulness of a modification of the Lichtenstein hernioplasty procedure by evaluating its impact on postoperative discomfort. From December 1999 to May 2006, the Lichtenstein inguinal hernioplasty was performed in 406 patients with noncomplicated unilateral inguinal hernia. During reconstruction, the mesh was fixed to the inguinal canal floor without stitching its upper margin to the internal oblique muscle. Control of postoperative pain proved to be satisfactory; 72 hours after surgery, 26.1 per cent of patients no longer felt any pain, whereas 54.4 per cent had slight pain without the need for painkillers; on Day 7, 92.8 per cent felt no pain at …

AdultMalemedicine.medical_specialtyAdolescentPostoperative paininguinal hernia repair Lichtenstein postoperative discomfortHernia InguinalQuality of lifemedicineHumansHerniaInguinal hernioplastyAgedPain MeasurementAged 80 and overPain PostoperativeChi-Square Distributionbusiness.industryChronic painRecovery of FunctionGeneral MedicineMiddle AgedSurgical Meshmedicine.diseaseInguinal canalSurgerySettore MED/18 - Chirurgia GeneraleInguinal herniaTreatment OutcomeSurgical meshmedicine.anatomical_structureAnesthesiaFemalebusiness
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Modified fixation free plug technique using a new 3D multilamellar implant for inguinal hernia repair: a retrospective study of a single operator cas…

2013

Aim: Implant fixation, mesh shrinkage and poor quality of tissue ingrowth are unresolved issues in modern hernia repair. Many complications reported in the literature such as bleeding, nerve entrapment, hematoma, pain, discomfort, and testicular complications, are considered to be a direct results of implant fixation. This article describes the outcomes of a procedure carried out using a handcrafted implant that addresses the issues consequent to point fixation. Methods: This was a retrospective study on the short, medium and long-term results of placing a-modified, fixation free three-dimensional polypropylene implant in 61 patients who underwent inguinal hernia repair using a novel delive…

AdultMalemedicine.medical_specialtyHerniaAdolescentmedicine.medical_treatmentprostheses and implantOperative TimeHernia InguinalPolypropylenesProsthesis DesignFixation (surgical)HematomaPostoperative ComplicationsRetrospective Studiemedicineprosthesis fixation.HumansHerniaHerniorrhaphyAgedRetrospective StudiesAged 80 and overPain Postoperativebusiness.industryHernia; Herniorrhaphy; Inguinal; Prostheses and implants; Prosthesis fixation; Adolescent; Adult; Aged; Aged 80 and over; Female; Hernia Inguinal; Herniorrhaphy; Humans; Male; Middle Aged; Operative Time; Pain Postoperative; Polypropylenes; Postoperative Complications; Prosthesis Design; Retrospective Studies; Treatment Outcome; Surgical Mesh; Surgery; Medicine (all)Medicine (all)Chronic painMiddle AgedSurgical Meshmedicine.diseaseHernia repairSurgeryInguinal herniaSettore MED/18 - Chirurgia GeneraleSurgical meshTreatment OutcomeinguinalSurgeryFemaleImplantPostoperative ComplicationbusinessProsthesis fixationPolypropylenehernia; inguinal; herniorrhaphy; prostheses and implants; prosthesis fixation.HumanHernia : the journal of hernias and abdominal wall surgery
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New mesh shape and improved implantation procedure to simplify and standardize open ventral hernia repair: a preliminary report.

2010

Introduction Issues in ventral hernia repair are represented by the need for mesh fixation and how to assure a sufficient mesh overlap of the defect. Aiming to resolve these problems, this study describes a modified technique for ventral and incisional hernia repair based upon a newly developed mesh with a special design. This new type of implant allows broader coverage of the abdominal wall and results in tension- and fixation-free repair. Materials and methods A unique geometrically shaped mesh consisting of a large central body and radiating arms was used to repair ventral or incisional hernia. The mesh was intended not to be point-fixated. The friction of the straps passing through the …

AdultMalemedicine.medical_specialtyHerniaFrictionIncisional herniaAbdominal wallProsthesis ImplantationHematomaPreliminary reportProstheseRecurrencemedicineHumansSurgical Wound InfectionHerniaHerniorrhaphyFixation (histology)AgedSurgical fixation deviceVentral hernia repairbusiness.industryAbdominal WallImplantMiddle AgedSurgical Meshmedicine.diseaseHernia VentralSurgerySettore MED/18 - Chirurgia Generalemedicine.anatomical_structureSeromaVentralSurgeryFemaleImplantbusinessFollow-Up StudiesHernia : the journal of hernias and abdominal wall surgery
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Tentacle-shaped mesh for fixation-free repair of umbilical hernias

2019

Purpose: Mesh fixation and broad overlap represent an open issue in umbilical hernia repair. A proprietary-designed implant with tentacle straps at its boundary has been developed to ensure a suture-free repair and a broader coverage of the abdominal wall. The study describes the results of umbilical hernia procedures carried out with the tentacle-shaped implant and the related surgical technique. Methods: A proprietary tentacle-shaped flat mesh having a central body with integrated radiating arms at its edge was used to repair large umbilical hernias in 62 patients. The implant was placed in preperitoneal sublay. The friction of the straps, crossing the abdominal wall thanks to a special n…

AdultMalemedicine.medical_specialtyHerniaHow-I-Do-Itmedicine.medical_treatmentNavelProsthesisProsthesis ImplantationAbdominal wallFixation freeRecurrenceUmbilicalmedicineHumansHerniaFreexationFriction forceHerniorrhaphyAgedUmbilicusTentacle meshbusiness.industryAbdominal WallSuture TechniquesProstheses and ImplantsMiddle AgedSurgical Meshmedicine.diseaseHernia repairUmbilical herniaSurgerySurgical meshmedicine.anatomical_structureHernia repairFemaleSurgeryImplantbusinessHernia UmbilicalHernia
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Prophylactic Single-use Negative Pressure Dressing in Closed Surgical Wounds After Incisional Hernia Repair: A Randomized, Controlled Trial.

2020

OBJECTIVE A randomized controlled trial (RCT) was undertaken to evaluate whether the prophylactic application of a specific single-use negative pressure (sNPWT) dressing on closed surgical incisions after incisional hernia (IH) repair decreases the risk of surgical site occurrences (SSOs) and the length of stay. BACKGROUND The sNPWT dressings have been associated to several advantages like cost savings and prevention of SSOs like seroma, hematoma, dehiscence, or wound infection (SSI) in closed surgical incisions. But this beneficious effect has not been previously studied in cases of close wounds after abdominal wall hernia repairs. METHODS An RCT was undertaken between May 2017 and January…

AdultMalemedicine.medical_specialtyIncisional herniamedicine.medical_treatment03 medical and health sciences0302 clinical medicineHematomaPostoperative ComplicationsNegative-pressure wound therapyMedicineHumansIncisional HerniaHerniaProspective StudiesHerniorrhaphyAgedbusiness.industryWound dehiscenceSurgical woundMiddle Agedmedicine.diseaseHernia repairSurgery030220 oncology & carcinogenesisSeroma030211 gastroenterology & hepatologySurgeryFemalebusinessNegative-Pressure Wound TherapyAnnals of surgery
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Botulinum toxin to avoid component separation in midline large hernias.

2020

Abstract Background The goal of our study was to compare results in patients with large midline incisional hernia using modified anterior component separation versus preoperative botulinum toxin and following Rives repair, with a focus on surgical site occurrences, possibility of fascial closure, duration of hospital stay, and hernia recurrence rate. Methods From to March 2016 to June 2019, a prospective comparative study was performed in 80 consecutive patients with large midline incisional hernias and hernia transverse diameters between 11 and 17 cm under elective hernia repair at our tertiary center. Two groups were analyzed prospectively: 40 patients with preoperative botulinum toxin ad…

AdultMalemedicine.medical_specialtyIncisional herniamedicine.medical_treatment030230 surgeryInjections Intramuscular03 medical and health sciences0302 clinical medicineSurgical sitePreoperative CaremedicineHumansIncisional HerniaHerniaIn patientProspective StudiesBotulinum Toxins Type AHerniorrhaphyAbdominal MusclesAgedSurgical repairbusiness.industryAbdominal WallMiddle AgedHernia repairmedicine.diseaseBotulinum toxinComponent separationHernia VentralSurgeryElective Surgical Procedures030220 oncology & carcinogenesisSurgeryFemalebusinessTomography X-Ray Computedmedicine.drugSurgery
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Acute inflammatory response in the subcutaneous versus periprosthethic space after incisional hernia repair: an original article.

2014

BACKGROUND: The acute inflammatory response following mesh implantation has been often evaluated in vitro and in animal models. The aim of this study was to evaluate the acute inflammatory response near the prosthesis in human by analysing some inflammatory indicators.METHODS: We used a cohort of twelve male patients affected by midline incisional hernia, who were admitted for surgical mesh repair. A suction drain was placed between the mesh and rectal muscles whereas, the other one was placed between the subcutaneous tissue and the oblique external sheath. The acute inflammatory response was analyzed by measuring the production of interleukin [IL]-1, IL-10, IL-1ra, C-Reactive Protein (CRP)…

AdultMalemedicine.medical_specialtyIncisional herniamedicine.medical_treatmentAcute Disease; Adult; Biomarkers; C-Reactive Protein; Cytokines; Follow-Up Studies; Hernia Ventral; Herniorrhaphy; Humans; Inflammation; Male; Middle Aged; Surgical Mesh; Postoperative Complications; Medicine (all)InflammationProsthesisProsthesisFollow-Up StudiePostoperative ComplicationsDrain fluidmedicineHumansCytokineHerniorrhaphyInflammationbiologybusiness.industryMedicine (all)C-reactive proteinAlbuminInflammatory responseGeneral MedicineBiomarkerMiddle AgedSurgical Meshmedicine.diseaseHernia repairHernia VentralSurgerySettore MED/18 - Chirurgia GeneraleSurgical meshmedicine.anatomical_structureC-Reactive ProteinAcute Diseasebiology.proteinCytokinesHernia repairSurgeryPostoperative Complicationmedicine.symptombusinessBiomarkersSubcutaneous tissueHumanFollow-Up StudiesResearch ArticleBMC surgery
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Fertility in males after childhood, adolescent, and adult inguinal operations

2018

Abstract Background/purpose Inguinal hernia repair and orchidopexy are among the most common operations in boys. The impact on future fertility has not been conclusively defined. This study evaluates sperm quality after previous inguinal surgery. Methods Spermiograms of men with a desire to conceive children were analyzed. History of previous inguinal surgery (hernia repair, orchidopexy, varicocele ligation) was correlated with sperm quality. Other influential factors (age, BMI, chronic medication, tobacco use) were also tested. Results A total of 333 patients were included. Overall, 12.6% of the subjects had undergone previous inguinal surgery. Of these, 17 (43%) were inguinal hernia repai…

AdultMalemedicine.medical_specialtyMultivariate analysisTobacco useAdolescentmedicine.medical_treatmentmedia_common.quotation_subjectVaricoceleInguinal CanalHernia InguinalFertilityCohort StudiesYoung Adult03 medical and health sciencesPostoperative Complications0302 clinical medicine030225 pediatricsVaricoceleHumansMedicineProspective StudiesChildLigationHerniorrhaphyAgedmedia_commonbusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseHernia repairSpermSurgerySemen AnalysisInguinal herniaFertilityChild PreschoolOrchiopexy030220 oncology & carcinogenesisPediatrics Perinatology and Child HealthSurgeryVaricocele ligationbusinessJournal of Pediatric Surgery
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